A paper released in the January 2021 edition in Frontiers in Autoimmunity, tested the autoimmune response to COVID-19 on 55 target tissues and organs. They found that “SARS-CoV-2 antibodies had reactions with 28 out of 55 tissue antigens, representing a diversity of tissue groups that included barrier proteins, gastrointestinal, thyroid and neural tissues, and more. “
This implies is that if there is a genetic susceptibility or tendency to an autoimmune condition, and you have an immune response to the virus, you may be triggering an autoimmune response to that particular tissue.
This could help explain the diverse symptoms and outcomes associated with COVID infections and possibly the “long haul syndrome” that some folks with COVID are experiencing..
“Extensive immune cross-reactivity between SARS-CoV-2 antibodies and different antigen groups may play a role in the multi-system disease process of COVID-19, influence the severity of the disease, precipitate the onset of autoimmunity in susceptible subgroups, and potentially exacerbate autoimmunity in subjects that have pre-existing autoimmune diseases.”